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First, as I previously reviewed, these are gigantic pills, not "caplets" as advertised. The most annoying thing tho is that they explode in my pill pack. Like many, I sort my prescriptions and supplements into a weekly day by day pack. While these pills are fine in their original packaging with a bunch of silica gel packets in it. Put them in your weekly package, and by the time you get to Friday, the pills have exploded into piles of powder. This has gotten worse and worse as the bottle has gotten older. I will NEVER buy these again, and will throw out the ones I have over this.
For those who experience overactive bladder or interstitial bladder, be aware that this product contains acidic ingredients that are known irritants that can exacerbate these disorders causing frequent urination issues. This is endemic to many supplement over the counter preparations.