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I tried opening a 20 capsule and I just dabbed a little with my finger for a week. Seemed ok. Then I took one capsule and my BP SPIKED to dangerous levels and would not come down. I experienced Extreme pressure in my head and headache that lasted two days. Nervousness, terrible nervousness that lasted for days and felt like someone beat me up, my entire body was exhausted. I could not even get out of bed. Pain in my kidneys and adrenals. Just severe reaction. I cannot take that stuff.
I didn’t know what to expect when I started Pqq. After a week or so my allergies began to improve, All of the other benefits I truly didn’t notice yet too soon. My allergies are crazy all year round and this works better than Benadryl, Zyrtec, Etc... and it’s natural...
I started buying this after going off Lipitor because of muscle weakness and fatigue. I read that PQQ helps repair mitochondria and thought I might as well try it. I am feeling much better after two months -- I actually began feeling better after six days. I plan on staying on PQQ along with Co-Q-10. If you take a statin, I recommend both, but do your own research. You can't necessarily trust your doctor, though, because they are sometimes in the pocket of Big Pharma.
I thought I was wasting my time with this stuff, until I quit using it. All the energy required to work out suddenly wasn't there. I started using it again, and presto changeo, the energy AND motivation were back. I was actually surprised at the immediate difference. This little pill actually works. And it works the same day. Again, this little pill is surprising and actually makes a difference.